If you are wondering why the entries of events and peoples in the north at the beginning, that is because it is from there that the ancestors of the Cherokee came in the mid-seventeenth century, certainly the Erie with a hefty contribution from the Huron, both once large and powerful confederacies in the Great Lakes region that fell to the war packs of the Haudenosaunee of the Five Nations.
1649 - After the Haudenosaunee destroy two of their mission towns following many years of brutal warfare, the Huron burn their remaining fifteen and leave their area, some joining with the Petun, the rest fleeing to sanctuary with the Erie and the Chonnonton (Neutrals). At the end of the year, the Iroquois destroy the Petun, some of whom migrate west with the Huron among them to become the Wyandot.
1688 - Franquelin produces another map of La Louisiane showing the following towns or tribes on the upper Kaskinampo River: Tchalak, Tamghi, Cattoughi.
Late 1680’s-early 1690’s – Cherokee begin cautiously migrating north back to the now deserted Allegheny-Upper Ohio Valley from which they came, centering on the town of Allegheny at the confluence of the Kiskiminetas and Allegheny Rivers, what is now Schenley, Pennsylvania.
1735 - According to James Adair in History of the American Indians published in 1775, the Cherokee at this time had sixty-four towns and villages, with about six thousand warriors, making a population of roughly twenty-four thousand.
For convenience of organizing trade with the Cherokee, South Carolina divides the thirty-eight towns of the nation into six districts: Overhills, Valley, Middle, Keowee, Out, and Lower.
1766 - The Moravian Brethren produce a map dividing the Cherokee towns into four groups: the Upper Settlements, with 19 towns; the Valley Settlements, with 5 or 6 towns; the Lower Settlements, with 9 towns; and the Middle Settlements, with 5 towns. That is 38 or 39 in all.
Dragging Canoe leads his people further westward and southwestward into what becomes known as the Five Lower Towns area, eventually penetrating Northeast Alabama as more Cherokee refugees migrate to the area.
Treaty of Dumplin Creek with the Free State of Franklin.
1786 - Treaty of Coyatee with the Free State of Franklin.
7 November 1794 – Treaty of Tellico Blockhouse, ending the Cherokee part in the Indian Wars of the Old Southwest.
1797 - The National Council alters Cherokee law to make it so that a killing that is not premeditated does not have to be avenged by the clan of the dead person.
1799 - The distribution roll of Cherokee annuities for this year shows fifty-one towns and villages in the nation.
1807 - A group of Cayuga sell their lands in New York and join the Seneca on the Sandusky. Other newcomers include Lenape and Wyandot (Huron).
Tecumseh's War begins.
Black Fox dies and is succeeded as principal chief by Pathkiller, with Charles R. Hicks as assistant principal chief.
1831 - The Seneca on the Sandusky sell their lands in Ohio and move to Oklahoma to live with the Cherokee Nation West.
1832 - The Mixed Band of Seneca and Shawnee in Ohio sell their lands and move to live with the "Seneca" formerly of Sandusky. Together, they are recognized as the United Nation of Seneca and Shawnee.
The negotiating committee reports the results to the full council (all persons present) gathered at New Echota, which approves the treaty unanimously. The Treaty of New Echota specifying terms and conditions for Cherokee removal to the west of the Mississippi river is then signed by Major Ridge, Elias Boudinot, James Foster, Testaesky, Charles Moore, George Chambers, Tahyeske, Archilla Smith, Andrew Ross, William Lassley, Caetehee, Tegaheske, Robert Rogers, John Gunter, John A. Bell, Charles Foreman, William Rogers, George W. Adair, James Starr, and Jesse Halfbreed.
(A few decades later, the Mormon Church was allotting $45 to bring members all the way from England to Utah.)
1839-1844 - The Regulator-Moderator War in East Texas.
1867 - The Eastern Shawnee Tribe (now "of Oklahoma") separates from the United Nation of Seneca and Shawnee, which becomes the Seneca Tribe of Indian Territory.
1881 - A band of Cayuga from Canada join the Seneca Tribe in Indian Territory.
26 June 1936 - The current Seneca-Cayuga Nation is recognized as the Seneca-Cayuga Tribe of Oklahoma, changing its name in 2014.